New Study Strengthens Association Of Prostate Cancer With Exposure To Agent Orange In Vietnam Veterans What is Doxepin? The Eurosearchengine

New Study Strengthens Association Of Prostate Cancer With Exposure To Agent Orange In Vietnam Veterans

As men age, their risk of developing prostate cancer increases. Aging Vietnam veterans are giving researchers new opportunities to solidify connection between in-country exposure to Agent Orange and subsequent prostate cancer development. In a study presented during Annual Scientific Meeting of the American Urological Association ( AUA ) in Orlando, researchers presented data from a large study of veterans enrolled in Northern California VA System, examining prostate cancer incidence and disease characteristics in those exposed to Agent Orange compared to those who weren't exposed.

Researchers will present their findings to media during a special press conference on May 18 at 2: 30 p. m.

More than 13, 000 Vietnam Veterans were divided into two groups based on their exposure to Agent Orange. Twice as many men exposed to Agent Orange were identified with prostate cancer. Agent Orange-exposed men were also diagnosed younger and were more likely to present with aggressive or metastatic disease. Other prostate cancer risk factors race, body-mass index ( BMI ) and smoking were not statistically different between two groups.

This increased evidence suggests that exposure to Agent Orange should be considered a risk factor for developing prostate cancer, similar to African-American heritage or a family history of disease.

About Agent Orange: Agent Orange is a combination of two synthetic compounds known to be contaminated with the dioxin tetrachlorodibenzo-para-dioxin ( TCDD ) during the manufacturing process. Named for color of the barrel in which it was stored, Agent Orange was one of many broad-leaf defoliants used in Vietnam to destroy enemy ground cover. It is estimated that more than 20 million gallons of chemicals, also known as " rainbow herbicides, " were used between 1962 and 1971; approximately half of herbicides were Agent Orange. In 1997, the International Agency for Research on Cancer re-classified TCDD as a Group 1 carcinogen, a classification that includes arsenic, asbestos and gamma radiation.

In addition to author, Christopher L. Amling, M. D. , a member of the AUA Public Media Committee, will be on hand to provide expert commentary on studies.

Chamie K, deVere White RW, Ellison LM: Agent Orange exposure, Vietnam War veterans and risk of prostate cancer. J Urol , suppl. , 2008; 179: 149, abstract 421.

About American Urological Association: Founded in 1902 and headquartered near Baltimore, Maryland, American Urological Association is pre-eminent professional organization for urologists, with more than 15, 000 members throughout the world. An educational nonprofit organization, AUA pursues its mission of fostering the highest standards of urologic care by carrying out a wide variety of programs members and their patients, including UrologyHealth. org, an award-winning on-line patient education resource, and the American Urological Association Foundation, Inc.

American Urological Association ( AUA ) 1000 Corporate Blvd. Linthicum, MD 21040 United States http: //www. auanet. org

What is Doxepin?

uses of Doxepin Doxepin is used to treat mental/mood problems such as depression, anxiety and bipolar disorder. It may help improve mood and feelings of well-being, relieve anxiety and tension, help we sleep better, and increase your energy level. Doxepin belongs to a class of medications called tricyclic antidepressants. It works by affecting balance of certain natural chemicals ( neurotransmitters ) in brain.

how to use of Doxepin Read Medication Guide available from your pharmacist. Consult your doctor or pharmacist if you have any questions.

Take Doxepin by mouth, usually 1 to 3 times daily or as directed by your doctor. If we take it only once a day, take it at bedtime to help reduce daytime sleepiness. The dosage is based on your age, medical condition and response to therapy. Your doctor may start we at a low dose and gradually increase your dose over several weeks. Follow your doctor's instructions carefully.

Use dropper that comes with medication to measure out the prescribed amount. Just before taking, mix drug with half a glass ( 4 ounces or 120 milliliters ) of water, whole/skim milk, or orange, grapefruit, tomato, prune or pineapple juice, and drink all of the mixture. Don't mix with soda or other carbonated beverages. If you are taking Doxepin in combination with liquid methadone, we may mix both drugs with lemonade, orange juice, sugar water, orange drink mix, or plain water, but not grape juice. Mix only what we need for each dose. Don't prepare a supply for future use.

Doxepin doesn't work right away. It may take up to 2 to 3 weeks before you experience full benefits.

Use Doxepin regularly in order to get the most benefit from it. To help we remember, take it at the same times each day.

It's important to continue taking Doxepin even if you feel well. Don't suddenly stop taking Doxepin without consulting your doctor. Some conditions may become worse when the drug is abruptly stopped. Muscle aches, headaches and worsening anxiety may also occur. Your dose may need to be gradually decreased.

Tell your doctor if your condition persists or worsens.

other used of Doxepin This section contains uses of Doxepin that aren't listed in approved professional labeling for drug but that may be prescribed by your health care professional. Use Doxepin for a condition that's listed in this section only if it has been so prescribed by your health care professional.

If directed by your doctor, Doxepin may also be used to treat certain types of pain ( e. g. , peripheral neuropathy, neuropathic pain ) and trouble sleeping.

side effects of Doxepin See also the Warning section.

Drowsiness, dizziness, dry mouth, blurred vision, constipation, fast heartbeat, nausea, vomiting, loss of appetite, changes in taste, weight gain, or trouble urinating may occur while use Doxepin. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

To relieve dry mouth, suck on ( sugarless ) hard candy or ice chips, chew ( sugarless ) gum, drink water, or use a saliva substitute.

Remember that your doctor has prescribed Doxepin because he or she has judged that benefit to we is greater than the risk of side effects. Many people using Doxepin don't have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

Tell your doctor immediately if any of these rare but very serious side effects occur:

A very serious allergic reaction to Doxepin is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include:

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

precautions of Doxepin See also Warning section.

Before taking Doxepin, tell your doctor or pharmacist if you're allergic to it, or to other tricyclic antidepressants ( e. g. , amitriptyline ) , or if you have any other allergies.

Doxepin shouldn't be used if we have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:

Before using Doxepin, tell your doctor or pharmacist your medical history, especially of:

Doxepin may make we drowsy or dizzy or cause blurred vision; use caution engaging in activities requiring alertness or clear vision such as driving or using machinery. Limit alcoholic beverages.

To minimize dizziness and the risk of fainting, get up slowly when rising from a sitting or lying position.

Before having surgery, tell your doctor or dentist that you're taking Doxepin.

Doxepin may make we more sensitive to sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Wear sunblock ( SPF 30 or greater ) and a hat when outdoors.

If we have diabetes, Doxepin may increase your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor immediately if we have symptoms such as increased thirst/urination, shakiness, unusual sweating, or hunger. Your anti-diabetic medication or diet may need to be adjusted.

Depression can lead to thoughts/attempts of suicide. Tell your doctor immediately if we have any suicidal thoughts, worsening depression, or any other mental/mood changes ( including new or worsening anxiety, agitation, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, rapid speech ) . Keep all medical appointments so your doctor can monitor your progress closely and adjust your medication if needed.

Caution is advised when using Doxepin in elderly because they may be more sensitive to its side effects, especially dizziness, drowsiness, confusion, and difficulty urinating.

Caution is advised when using Doxepin in children. ( See also Warning section. ) Doxepin should be used only when clearly needed during pregnancy. Discuss risks and benefits with your doctor.

Doxepin passes into breast milk and may have undesirable effects on a nursing infant. Breast-feeding while using Doxepin is not recommended. Consult your doctor before breast-feeding.

interactions of Doxepin Your healthcare professionals ( e. g. , doctor or pharmacist ) may already be aware of any possible drug interactions and may be monitoring we for it. Don't start, stop or change dosage of any medicine before checking with them first.

Doxepin shouldn't be used with the following medications because very serious ( possibly fatal ) interactions may occur:

Avoid taking MAO inhibitors within 2 weeks before and after treatment with Doxepin. In some cases a serious, possibly fatal drug interaction may occur while use Doxepin.

If you're currently using any of these medications listed above, tell your doctor or pharmacist before starting Doxepin.

Other drugs besides Doxepin that may affect heart rhythm ( QT prolongation in EKG ) include disopyramide, cisapride, halofantrine, pimozide among others. Before taking Doxepin, report all medications we are currently using to your doctor or pharmacist. QT prolongation can infrequently result in serious ( rarely fatal ) fast/irregular heartbeat and other symptoms ( e. g. , severe dizziness, fainting ) that require immediate medical attention. Ask your doctor or pharmacist for more details and for instructions on how we may reduce risk of this effect.

Before using Doxepin, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

If we have been taking fluoxetine, wait at least 5 weeks after stopping fluoxetine before starting Doxepin.

Cigarette smoking decreases blood levels of this medication. Tell your doctor if we smoke or if you have recently stopped smoking.

Tell your doctor or pharmacist if we also take drugs that cause drowsiness such as:

Check the labels on all your medicines ( e. g. , cough-and-cold products ) because they may contain drowsiness-causing ingredients. Ask your pharmacist about safe use of those products.

Also report use of drugs which might increase seizure risk ( decrease seizure threshold ) when combined with Doxepin such as bupropion, isoniazid ( INH ) , theophylline, or tramadol, among others. Consult your doctor or pharmacist for details.

This document doesn't contain all possible interactions. Therefore, before using Doxepin, tell your doctor or pharmacist of all products we use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.